Concepedia

PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1

Santiago Hernández-Pérez, Stéphane Koundrioukoff, Michelle Debatisse, Dong-Sung Kim, Marcus B. Smolka, Raimundo Freire, David A. Gillespie

Oncogene · 2016 · 48 citations · 21 references

DOI

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References

21

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

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Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

Heather P. Harding, Isabel Novoa, Yuhong Zhang et al. · Molecular Cell · 2000 · 3.2K citations · Full text

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Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response

Heather P. Harding, Yuhong Zhang, Anne Bertolotti et al. · Molecular Cell · 2000 · 2K citations · Full text

, , +15

The impact of the unfolded protein response on human disease

Shiyu Wang, Randal J. Kaufman · The Journal of Cell Biology · 2012 · 994 citations · Full text

, , +17

PERK mediates cell-cycle exit during the mammalian unfolded protein response

Joseph W. Brewer, J. Alan Diehl · Proceedings of the National Academy of Sciences · 2000 · 466 citations · Full text

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