Comparison of Succinimidyl [125I]Iodobenzoate with Iodogen Iodination Methods to Study Pharmacokinetics and ADME of Biotherapeutics

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

A.E. Bolton, W. M. Hunter · Biochemical Journal · 1973 · 3.3K citations · Full text

Recommendations for the Bioanalytical Method Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Macromolecules

Binodh DeSilva, Wendell C. Smith, Russell Weiner et al. · Pharmaceutical Research · 2003 · 610 citations

Molecular Docking, Ligand-binding Assays, Pharmacokinetic Modeling +11

Molecular SPECT Imaging: An Overview

Magdy M. Khalil, Jordi L. Tremoleda, T. Bayomy et al. · International Journal of Molecular Imaging · 2011 · 261 citations · Full text

Engineering, Oncologic Imaging, Imaging Agent +21

Trichloroacetic acid‐induced protein precipitation involves the reversible association of a stable partially structured intermediate

Dakshinamurthy Rajalingam, Charles Loftis, Jiashou J. Xu et al. · Protein Science · 2009 · 179 citations · Full text

Protein Assembly, Molecular Biology, Protein Phase Separation +18

A method for the radiohalogenation of proteins resulting in decreased thyroid uptake of radioiodine

Michael R. Zalutsky, Acharan S. Narula · International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes · 1987 · 175 citations

Thyroid Uptake, Biochemistry, Natural Sciences +12