Recommendations for the Bioanalytical Method Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Macromolecules

Binodh DeSilva, Wendell C. Smith, Russell Weiner, +6

Pharmaceutical Research

Molecular DockingLigand-binding AssaysPharmacokinetic ModelingBiochemistryPreclinical Drug Evaluation +9

Development, validation, and implementation of a multiplex immunoassay for the simultaneous determination of five cytokines in human serum

Chad Ray, Ronald R. Bowsher, Wendell C. Smith, +4

Journal of Pharmaceutical and Biomedical Analysis

InflammationAllergyAutoimmune DiseaseMedicineImmunodeficiencies +9

Workshop on Bioanalytical Methods Validation for Macromolecules: Summary Report

Krys J. Miller, Ronald R. Bowsher, Abbie Celniker, +20

Pharmaceutical Research

Recommendations for Systematic Statistical Computation of Immunogenicity Cut Points

Viswanath Devanarayan, Wendell C. Smith, Rocco L. Brunelle, +3

The AAPS Journal

VaccinationStatistical ComputingImmunophenotypingBiostatisticsPublic Health +3

Application of experimental design techniques to optimize a competitive ELISA

G. Sitta Sittampalam, Wendell C. Smith, Thomas W. Miyakawa, +2

Journal of Immunological Methods

Involvement of calcium channels in the sexual dimorphism of cadmium-induced hepatotoxicity

Thomas K. Baker, Heidi B. VanVooren, Wendell C. Smith, +1

Toxicology Letters

Cadmium-induced HepatotoxicityPhysiologyCalcium ChannelsToxicologyMetal Toxicity +1

Statistical power analysis for hemodynamic cardiovascular safety pharmacology studies in beagle dogs

Alan Y. Chiang, Wendell C. Smith, Bradley W. Main, +1

Journal of Pharmacological and Toxicological Methods

Animal PhysiologyVeterinary PhysiologyStatistical Power AnalysisCardiovascular DiseasePhysiology +10

A sensitive chemiluminescent enzyme immunoassay for the bioanalysis of carboxyl-terminal B-chain analogues of human insulin

Ying Cao, Wendell C. Smith, Ronald R. Bowsher

Journal of Pharmaceutical and Biomedical Analysis

Sensitive Chemiluminescent EnzymeBiochemistryBioanalysisImmunochemistryCarboxyl-terminal B-chain Analogues +4

Expression of TRPM-2 during involution and regeneration of the rat liver

Leah M. Helvering, Katherine K. Richardson, Deborah Horn, +5

Cancer Letters

InflammationSignal TransductionMolecular PhysiologyHepatologyCell Signaling +11

Delayed hypersensitivity to mumps antigen in humans

John Callaghan, Bruce H. Petersen, Wendell C. Smith, +2

Clinical Immunology and Immunopathology

AllergyImmunodeficienciesImmunologyOral ImmunotherapyAutoimmunity +4