Concepedia

RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4

Malek Najjar, Danish Saleh, Matija Zelic, Shoko Nogusa, Saumil Shah, Albert Tai, Joshua N. Finger, Apostolos Polykratis, Peter J. Gough, John Bertin,

Immunity · 2016 · 290 citations · 52 references

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52

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce et al. · Nature Chemical Biology · 2005 · 3K citations

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

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Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He, Lai Wang, Lin Miao et al. · Cell · 2009 · 2.2K citations

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RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

Duanwu Zhang, Jing Shao, Juan Lin et al. · Science · 2009 · 1.9K citations

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Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3

Huayi Wang, Liming Sun, Lijing Su et al. · Molecular Cell · 2014 · 1.6K citations · Full text

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