Peter J. Gough

Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death

Pontus Ørning, Dan Weng, Kristian K. Starheim et al. · Science · 2018 · 1K citations · Full text

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

William J. Kaiser, Haripriya Sridharan, Chunzi Huang et al. · Journal of Biological Chemistry · 2013 · 912 citations · Full text

Apoptosis, Immunology, Immune Regulation +23

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 803 citations

Systemic Activity, Medicine, Mechanism Of Action +4

MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

Yves Dondelinger, Wim Declercq, Sylvie Montessuit et al. · Cell Reports · 2014 · 797 citations · Full text

Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)

Kyle J. Garton, Peter J. Gough, Carl Blobel et al. · Journal of Biological Chemistry · 2001 · 629 citations