Concepedia

Recent developments of small molecule chemical probes for fluorescence-based detection of human carbonic anhydrase II and IX

Kanae Teruya, Kathryn F. Tonissen, Sally‐Ann Poulsen

MedChemComm · 2016 · 18 citations · 24 references

DOI

Concepts

Abstract

The increasingly sophisticated array of approaches for the specific labeling and fluorescence-based detection of carbonic anhydrase enzymes using small molecule affinity-based chemical probes is reviewed.

References

24

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The promise and peril of chemical probes

C.H. Arrowsmith, James E. Audia, Christopher P. Austin et al. · Nature Chemical Biology · 2015 · 836 citations · Full text

Hypoxia activates the capacity of tumor‐associated carbonic anhydrase IX to acidify extracellular pH

Eliška Švastová, Alžbeta Hulı́ková, Monika Rafajová et al. · FEBS Letters · 2004 · 698 citations · Full text

Preventing Thiol-Yne Addition Improves the Specificity of Strain-Promoted Azide–Alkyne Cycloaddition

Remon van Geel, Ger J.M. Pruijn, Floris L. van Delft et al. · Bioconjugate Chemistry · 2012 · 291 citations

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Carbonic Anhydrase Inhibitors. Design of Fluorescent Sulfonamides as Probes of Tumor-Associated Carbonic Anhydrase IX That Inhibit Isozyme IX-Mediated Acidification of Hypoxic Tumors

Alessandro Cecchi, Alžbeta Hulı́ková, J Pastorek et al. · Journal of Medicinal Chemistry · 2005 · 212 citations · Full text