Remon van Geel

Preventing Thiol-Yne Addition Improves the Specificity of Strain-Promoted Azide–Alkyne Cycloaddition

Remon van Geel, Ger J.M. Pruijn, Floris L. van Delft et al. · Bioconjugate Chemistry · 2012 · 295 citations

Life Sciences, Biochemistry, Molecular Biology +13

Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody–Drug Conjugates

Remon van Geel, Marloes A. Wijdeven, Ryan Heesbeen et al. · Bioconjugate Chemistry · 2015 · 270 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

The Redox State of Transglutaminase 2 Controls Arterial Remodeling

Jeroen van den Akker, Ed VanBavel, Remon van Geel et al. · PLoS ONE · 2011 · 51 citations · Full text

Life Sciences, Biochemistry, Physiology +13

Enzymatic glycan remodeling–metal free click (GlycoConnect™) provides homogenous antibody-drug conjugates with improved stability and therapeutic index without sequence engineering

Marloes A. Wijdeven, Remon van Geel, Jorin Hoogenboom et al. · mAbs · 2022 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmaceutics +17

A Polar Sulfamide Spacer Significantly Enhances the Manufacturability, Stability, and Therapeutic Index of Antibody–Drug Conjugates

Jorge M. M. Verkade, Marloes A. Wijdeven, Remon van Geel et al. · Antibodies · 2018 · 37 citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17