Concepedia

Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90

Su-Chan Lee, Hye‐Young Min, Hoon Choi, Ho Shin Kim, Kyong-Cheol Kim, So‐Jung Park, Myeong A Seong, Ji Hae Seo, Hyunju Park, Young‐Ger Suh,

Molecular Pharmacology · 2015 · 43 citations · 43 references

Concepts

MedicineOncologyPharmacologyCancer PharmacologyMolecular OncologyMolecular PharmacologyLung Cancer PharmacotherapyMolecular ChaperonesAnticancer ActivityAnticancer ChemotherapyAnticancer Natural ProductsChaperone InhibitorsHeat Shock Protein InhibitorsHsp90 Chaperone SystemMolecular Drug ResistanceProtein Binding In Oncology

References

43

Global cancer statistics

Ahmedin Jemal, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

Medicine, Oncology, Cancer Epidemiology +15

Cancer statistics, 2013

Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2013 · 11.9K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Physicochemical High Throughput Screening: Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption Processes

Manfred Kansy, Frank Senner, Klaus Gubernator · Journal of Medicinal Chemistry · 1998 · 1.3K citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

High throughput artificial membrane permeability assay for blood–brain barrier

Li Di, Edward H. Kerns, Kristi Fan et al. · European Journal of Medicinal Chemistry · 2003 · 1.1K citations

Pharmacy, Biomedical Engineering, Neuroscience +11

Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway

Jennifer S. Isaacs, Yunjin Jung, Edward G. Mimnaugh et al. · Journal of Biological Chemistry · 2002 · 659 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15