Cell Metabolism · 2016 · 436 citations · 36 references
Life SciencesBiochemistryMolecular BiologyCellular MetabolismMetabolismMitochondrial BiologyCellular RespirationMitochondrial BiochemistryMitochondrial BioenergeticsMitochondrial MetabolismMitochondrial PhysiologyOne-carbon MetabolismFolate BiosynthesisFolate CatabolismFolate HomeostasisOne-carbon Flux RegulationOne-carbon Pathways
36
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek, Konrad J. Karczewski, Eric Vallabh Minikel et al. · Nature · 2016 · 10.3K citations · Full text
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin et al. · Cell · 2013 · 3.4K citations · Full text
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
Richard Possemato, Kevin M. Marks, Yoav D. Shaul et al. · Nature · 2011 · 1.7K citations · Full text
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain, Roland Nilsson, Sonia Sharma et al. · Science · 2012 · 1.5K citations · Full text