Concepedia

The flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer’s disease

Xunhu Gu, Lijun Xu, Zhiqiang Liu, Bo Wei, Yuan‐Jian Yang, Guogang Xu, Xiaoping Yin, Wei Wang

Behavioural Brain Research · 2016 · 112 citations · 57 references

DOI

Concepts

References

57

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva et al. · Nature · 2002 · 4.3K citations

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β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

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Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Ganesh M. Shankar, Shaomin Li, Tapan Mehta et al. · Nature Medicine · 2008 · 3.7K citations · Full text

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Soluble pool of A? amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

Catriona McLean, Robert A. Cherny, Fiona Fraser et al. · Annals of Neurology · 1999 · 1.8K citations

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Purification and cloning of amyloid precursor protein β-secretase from human brain

Sukanto Sinha, John P. Anderson, Robin Barbour et al. · Nature · 1999 · 1.6K citations

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