Concepedia

Synaptic Plasticity Decline

Synaptic Plasticity Decline is a neurobiological phenomenon characterized by the progressive reduction in the capacity of synapses to strengthen or weaken in response to activity, which underlies age-related impairments in learning, memory, and neural adaptability within the context of neuroimmune aging.

622

Publications

52.5K

Citations

3.9K

Authors

1K

Institutions

Publications per year

2017–2026

218

Parents

Publications

622

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

Ronald S. Duman, George K. Aghajanian, Gerard Sanacora et al. · Nature Medicine · 2016 · 1.7K citations

, , +16

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

Juha Laurén, David A. Gimbel, Haakon B. Nygaard et al. · Nature · 2009 · 1.5K citations · Full text

, , +16

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

Saul Villeda, Kristopher E. Plambeck, Jinte Middeldorp et al. · Nature Medicine · 2014 · 1.1K citations · Full text

, , +17

Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment

Stephen W. Scheff, D. A. Price, Frederick A. Schmitt et al. · Neurobiology of Aging · 2005 · 1K citations

, , +16

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

Michael Saxe, Fortunato Battaglia, Jing-Wen Wang et al. · Proceedings of the National Academy of Sciences · 2006 · 1K citations

, , +17

1–5 of 622

Authors

3.9K

  1. RM
    Ruth M. Barrientos

    University of Colorado Boulder, United States

    7 publications · 798 citations

    7

    h-index

  2. SF
    Steven F. Maier

    University of Colorado Boulder, United States

    6 publications · 770 citations

    6

    h-index

  3. GL
    Gary Lynch

    University of California, Irvine, United States

    6 publications · 468 citations

    6

    h-index

  4. DR
    Di‐Yun Ruan

    University of Science and Technology of China, China

    6 publications · 175 citations

    6

    h-index

  5. AK
    Alfredo Kirkwood

    Johns Hopkins University, United States

    5 publications · 1.4K citations

    5

    h-index

1–5 of 3.9K

Institutions

1K

  1. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    71 publications

    7.9K citations

  2. Inserm

    Paris, France

    16 h-index

    79 publications

    4.9K citations

  3. New York University

    New York, United States

    14 h-index

    33 publications

    4.8K citations

  4. University of California, Irvine

    Irvine, United States

    14 h-index

    75 publications

    5.8K citations

  5. Trinity College Dublin

    Dublin, Ireland

    13 h-index

    44 publications

    4.1K citations

  6. Harvard University

    Cambridge, United States

    13 h-index

    27 publications

    5.5K citations

  7. Fondazione Santa Lucia

    Rome, Italy

    12 h-index

    60 publications

    4K citations

  8. Columbia University

    New York, United States

    12 h-index

    41 publications

    16.8K citations

1–8 of 1K

Venues

  1. Journal of Neuroscience

    38 publications · 5.3K citations

    34

    h-index

  2. Neurobiology of Aging

    42 publications · 3.8K citations

    31

    h-index

  3. Neuroscience

    23 publications · 1.8K citations

    23

    h-index

  4. Neurobiology of Disease

    21 publications · 1.7K citations

    20

    h-index

  5. Brain Research

    22 publications · 1.4K citations

    18

    h-index

1–5