Methods in molecular biology · 2014 · 36 citations · 17 references
Life SciencesGeneticsMolecular BiologyGenetic EngineeringGenome EditingMolecular BiotechnologyCrispr-based EngineeringCrispr-cas SystemsClustered Regularly Interspaced Short Palindromic Repeats (Crispr)-based MutagenesisEndonuclease MechanismsRestriction EndonucleasesStructure-specific Endonucleases
17
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
Fyodor D. Urnov, Jeffrey C. Miller, Ya-Li Lee et al. · Nature · 2005 · 1.6K citations
Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases
Aron M. Geurts, Gregory J. Cost, Yevgeniy Freyvert et al. · Science · 2009 · 919 citations · Full text
Enhancing Gene Targeting with Designed Zinc Finger Nucleases
Marina Bibikova, Kelly J. Beumer, Jonathan K. Trautman et al. · Science · 2003 · 815 citations