Concepedia

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

Fyodor D. Urnov, Jeffrey C. Miller, Ya-Li Lee, Christian Beauséjour, Jeremy M. Rock, Sheldon Augustus, Andrew C. Jamieson, Matthew H. Porteus, Philip D. Gregory, Michael C. Holmes

Nature · 2005 · 1.6K citations · 25 references

DOI

Concepts

References

25

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Marina Cavazzana, Salima Hacein‐Bey, Geneviève de Saint Basile et al. · Science · 2000 · 2.6K citations

, , +17

Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes.

Jim Miller, A. McLachlan, A. Klug · The EMBO Journal · 1985 · 2.5K citations · Full text

, , +14

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

Nikola P. Pavletich, Carl O. Pabo · Science · 1991 · 2.1K citations

, , +15

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Y G Kim, Srinivasan Chandrasegaran · Proceedings of the National Academy of Sciences · 1996 · 2.1K citations

, , +15

Targeted Chromosomal Cleavage and Mutagenesis in Drosophila Using Zinc-Finger Nucleases

Marina Bibikova, Kent G. Golic, Dana Carroll · Genetics · 2002 · 858 citations

, , +17