The B-cell tumor promoter Bcl-3 suppresses inflammation-associated colon tumorigenesis in epithelial cells

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Florian R. Greten, Lars Eckmann, Tim F. Greten et al. · Cell · 2004 · 2.4K citations · Full text

Medicine, Immunology, Oncology +16

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei I. Grivennikov, Eliad Karin, Janoš Terzić et al. · Cancer Cell · 2009 · 2.1K citations · Full text

Life Sciences, Immunology, Oncology +16

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

Hasan Zaki, Kelli L. Boyd, Peter Vogel et al. · Immunity · 2010 · 976 citations · Full text

Life Sciences, Immunology, Pathology +16

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

Julia Bollrath, Toby J. Phesse, Vivian A. von Burstin et al. · Cancer Cell · 2009 · 939 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis

Robert J. Moore, David M. Owens, Gordon Stamp et al. · Nature Medicine · 1999 · 836 citations

Medicine, Dermatology, Oncology +12