Antiproliferative activity and apoptosis inducing effects of nitric oxide donating derivatives of evodiamine

Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents

Shengzheng Wang, Kun Fang, Guoqiang Dong et al. · Journal of Medicinal Chemistry · 2015 · 196 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

Guoqiang Dong, Shengzheng Wang, Zhenyuan Miao et al. · Journal of Medicinal Chemistry · 2012 · 185 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells

Cécile Corbière, Bertrand Liagre, Faraj Terro et al. · Cell Research · 2004 · 169 citations

Life Sciences, Cell Biology, Oncology +17

Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells

Han-Chieh Ko, Yea-Hwey Wang, Kuo‐Tong Liou et al. · European Journal of Pharmacology · 2006 · 136 citations

Life Sciences, Immunology, Pharmacology +15

Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus , in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo

Cho-Hwa Liao, Shiow‐Lin Pan, Jih‐Hwa Guh et al. · Carcinogenesis · 2005 · 130 citations · Full text

Medicine, Oncology, Pharmacology +16