Genetic alteration of the α2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels

Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

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András Nagy, Janet Rossant, Roland Nagy et al. · Proceedings of the National Academy of Sciences · 1993 · 2.4K citations

Life Sciences, Biology, Genetics +16

Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.

Tom Curran, M B Gordon, Kathleen L. Rubino et al. · PubMed · 1987 · 627 citations

Life Sciences, Molecular Biology, Molecular Genetics +10

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

Rolf-Peter Ryseck, Syu-ichi Hirai, Moshé Yaniv et al. · Nature · 1988 · 574 citations

Life Sciences, Cell Biology, Molecular Biology +15

Central Hypotensive Effects of the α _2a -Adrenergic Receptor Subtype

Leigh B. MacMillan, Lutz Hein, Marta S. Smith et al. · Science · 1996 · 493 citations

Medicine, Neuroscience, Pharmacology +17