Leigh B. MacMillan

Central Hypotensive Effects of the α _2a -Adrenergic Receptor Subtype

Leigh B. MacMillan, Lutz Hein, Marta S. Smith et al. · Science · 1996 · 493 citations

Medicine, Neuroscience, Pharmacology +17

Substitution of a mutant α _2a -adrenergic receptor via “hit and run” gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses <i>in vivo</i>

Parul P. Lakhlani, Leigh B. MacMillan, Tian Z. Guo et al. · Proceedings of the National Academy of Sciences · 1997 · 366 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Abnormal Regulation of the Sympathetic Nervous System in α_2A-Adrenergic Receptor Knockout Mice

John D. Altman, Anne U. Trendelenburg, Leigh B. MacMillan et al. · Molecular Pharmacology · 1999 · 332 citations

Life Sciences, Neuroscience, Physiology +17

The α_2aAdrenergic Receptor Subtype Mediates Spinal Analgesia Evoked by α₂Agonists and Is Necessary for Spinal Adrenergic–Opioid Synergy

Laura S. Stone, Leigh B. MacMillan, Kelley F. Kitto et al. · Journal of Neuroscience · 1997 · 292 citations · Full text

Medicine, Neuroscience, Pharmacology +17

CaM kinase augments cardiac L-type Ca²⁺current: a cellular mechanism for long Q-T arrhythmias

Yuejin Wu, Leigh B. MacMillan, R. Blair McNeill et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1999 · 135 citations

Life Sciences, Cardiology, Physiology +17