Calmodulin kinase II inhibition protects against structural heart disease

Rong Zhang, Michelle S.C. Khoo, Yuejin Wu, +16

Nature Medicine

CardiomyopathyHeart FailureMolecular PhysiologyStructural Heart DiseaseCardiovascular Disease +7

Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels

Igor Dzhura, Yuejin Wu, Roger Colbran, +2

Nature Cell Biology

Molecular PhysiologySignal TransductionPhysiologyCytoskeletonCalmodulin Kinase +5

Calmodulin Kinase II and Arrhythmias in a Mouse Model of Cardiac Hypertrophy

Yuejin Wu, Joel Temple, Rong Zhang, +8

Circulation

MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells

Tingting Ren, H Zhang, J Wang, +9

Oncogene

Cancer ResearchMitochondrial FunctionHcc CellsCell BiologyReactive Oxygen Specie +7

KN-93, an Inhibitor of Multifunctional Ca++/Calmodulin-Dependent Protein Kinase, Decreases Early Afterdepolarizations in Rabbit Heart

Mark E. Anderson, Andrew P. Braun, Yuejin Wu, +1

Journal of Pharmacology and Experimental Therapeutics

RETRACTED: L-Type Ca2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII

Chad E. Grueter, Sunday A. Abiria, Igor Dzhura, +5

Molecular Cell

ChannelopathiesMolecular PhysiologySignal TransductionBiochemistrySynaptic Signaling +10

Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease

Solena Le Scouarnec, Naina Bhasin, C Vieyres, +13

Proceedings of the National Academy of Sciences

Cardiac MuscleAnkyrin-b-dependent Ion ChannelHuman SndNode DiseaseCellular Physiology +18

Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart

Tyler P. Rasmussen, Yuejin Wu, Mei-ling A. Joiner, +21

Proceedings of the National Academy of Sciences

Calmodulin kinase II is required for fight or flight sinoatrial node physiology

Yuejin Wu, Zhan Gao, Biyi Chen, +11

Proceedings of the National Academy of Sciences

Cardiac MuscleHeart FailureCytoskeletonCardiovascular FunctionCellular Physiology +18

The mitochondrial uniporter controls fight or flight heart rate increases

Yuejin Wu, Tyler P. Rasmussen, Olha M. Koval, +9

Nature Communications