Adrenergic α_2C-Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice

Jukka Sallinen, Antti Haapalinna, Timo Viitamaa, +2

Journal of Neuroscience

PsychopharmacologyTargeted InactivationSocial SciencesNeuroendocrine MechanismBrain Dopamine +17

Genetic Alteration of α2C-Adrenoceptor Expression in Mice: Influence on Locomotor, Hypothermic, and Neurochemical Effects of Dexmedetomidine, a Subtype-Nonselective α2-Adrenoceptor Agonist

Jukka Sallinen, Richard E. Link, Antti Haapalinna, +9

Molecular Pharmacology

Genetic alteration of the α2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels

Jukka Sallinen, Antti Haapalinna, Ewen MacDonald, +5

Molecular Psychiatry

Clinical DisordersStress HormoneBehavioral NeuroscienceStressPhysiology +12

Evaluation of the effects of a specific α2-adrenoceptor antagonist, atipamezole, on α1- and α2-adrenoceptor subtype binding, brain neurochemistry and behaviour in comparison with yohimbine

Antti Haapalinna, Timo Viitamaa, Ewen MacDonald, +4

Naunyn-Schmiedeberg s Archives of Pharmacology

Molecular PharmacologyBehavioral NeuroscienceMedicineBehavioural PharmacologyBehavioral Pharmacology +11

Brain regional and adrenal monoamine concentrations and behavioral responses to stress in alcohol-preferring AA and alcohol-avoiding ANA rats

Esa R. Korpi, J. D. Sinclair, Petri Kaheinen, +3

Alcohol

Alcohol-preferring AaSubstance AbuseSubstance UseStress HormoneBehavioral Neuroscience +10

d-amphetamine and l-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the α2C-adrenergic receptor subtype

Jukka Sallinen, Antti Haapalinna, Timo Viitamaa, +2

Neuroscience

Molecular Pharmacologyα2C-adrenergic Receptor SubtypeL-5-hydroxytryptophan-induced BehavioursBehavioral NeuroscienceMedicine +12

The adrenergic α2 receptor and sexual incentive motivation in male rats

Timo Viitamaa, Antti Haapalinna, Anders Ågmo

Pharmacology Biochemistry and Behavior

Behavioral NeuroscienceMedicinePhysiologyNeuroendocrine MechanismNeuroendocrinology +8

In vitro and in vivo profiling of fadolmidine, a novel potent α2-adrenoceptor agonist with local mode of action

Jyrki Lehtimäki, Tiina Leino, Ari Koivisto, +5

European Journal of Pharmacology

Molecular PharmacologyVivo ProfilingBiochemistryMedicineLocal Mode +8

Comparison of the effects of acute and subchronic administration of atipamezole on reaction to novelty and active avoidance learning in rats

Antti Haapalinna, Ewen MacDonald, Timo Viitamaa, +3

Naunyn-Schmiedeberg s Archives of Pharmacology

Cognitive ScienceBehavioral NeuroscienceMedicineInhibitory ProcessAffective Neuroscience +11

Pharmacological profile of intrathecal fadolmidine, a α2-adrenoceptor agonist, in rodent models

Tiina Leino, Timo Viitamaa, Antti Haapalinna, +2

Naunyn-Schmiedeberg s Archives of Pharmacology

Molecular PharmacologyPharmacological StudyMedicineDrug DiscoveryPhysiology +7