Concepedia

CpG DNA and LPS induce distinct patterns of activation in human monocytes

Gunther Hartmann, A M Krieg

Gene Therapy · 1999 · 208 citations · 44 references

DOI

Concepts

References

44

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

, , +10

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations

, , +17

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

, , +17

CpG Oligodeoxynucleotides Act as Adjuvants that Switch on T Helper 1 (Th1) Immunity

Rose S. Chu, Oleg S. Targoni, Arthur Μ. Krieg et al. · The Journal of Experimental Medicine · 1997 · 1K citations · Full text

, , +16

Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants

Mark Roman, Elena Martín‐Orozco, Justin S. Goodman et al. · Nature Medicine · 1997 · 916 citations

, , +14