Replicating adenoviral vector–mediated transfer of a heat-inducible double suicide gene for gene therapy

An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

James R. Bischoff, David H. Kirn, Angelica Williams et al. · Science · 1996 · 1.8K citations

Mutant Adenovirus, Adenovirus Mutant, Functional P53 +13

Gene therapy - promises, problems and prospects

Inder M. Verma, Nikunj V. Somia · Nature · 1997 · 1.7K citations · Full text

Gene Therapies, Novel Therapy, Genetic Engineering +5

A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

Fadlo R. Khuri, John Nemunaitis, Ian Ganly et al. · Nature Medicine · 2000 · 1.1K citations

Intratumoral Onyx-015, Neck Cancer, Medicine +11

Regulation of the Erythropoietin Gene: Evidence That the Oxygen Sensor Is a Heme Protein

Mark A. Goldberg, Susan P. Dunning, H. Franklin Bunn · Science · 1988 · 1K citations

Iron Metabolism, Genetics, Redox Biology +20

Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.

Mark A. Goldberg, Thomas J. Schneider · Journal of Biological Chemistry · 1994 · 579 citations · Full text

Redox Biology, Oxidative Stress, Inflammation +17