Concepedia

Direct inhibition of oncogenic KRAS by Bacillus pumilus ribonuclease (binase)

О. N. Ilinskaya, Indrabahadur Singh, Elena Dudkina, Vera Ulyanova, Airat R. Kayumov, Guillermo Barreto

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2016 · 48 citations · 37 references

DOI

Concepts

References

37

ras oncogenes in human cancer: a review.

Joyce Bos · PubMed · 1989 · 5.1K citations

, , +17

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

J.M. Ostrem, Ulf Peters, Martin L. Sos et al. · Nature · 2013 · 2.5K citations · Full text

, , +14

Mammalian Ras interacts directly with the serine/threonine kinase raf

Anne B. Vojtek, Stanley M. Hollenberg, Jonathan A. Cooper · Cell · 1993 · 2K citations

, , +14

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

Klaus Scheffzek, Mohammad Reza Ahmadian, Wolfgang Kabsch et al. · Science · 1997 · 1.6K citations

, , +17

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Sean E. Egan, B.W. Giddings, Mary W. Brooks et al. · Nature · 1993 · 1.2K citations

, , +14