Organic Letters · 2010 · 31 citations · 10 references
Life SciencesBiochemistryMedicinal ChemistryFood ChemistryMetabolismMycologyBioactive Food ComponentsEndoplasmic Reticulum Stress-induced ApoptosisFatty Acid MetabolismOrganic AcidsEndoplasmic Reticulum StressEndoplasmic Reticulum Stress ApoptosisEndoplasmic Reticulum Stress ResponsesEndoplasmic Reticulum Stress-induced Cell DeathFungal Bioactive CompoundsMass Spectral Data Analysis
Five fatty acid amides, termitomycamides A to E (1 to 5), were isolated from the giant edible mushroom Termitomyces titanicus. The structures of 1-5 were determined by the interpretation of spectral data and/or synthesis. Compounds 2 and 5 showed protective activity against endoplasmic reticulum stress-dependent cell death.
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ORP150 protects against hypoxia/ischemia-induced neuronal death
Michio Tamatani, Tomohiro Matsuyama, Atsushi Yamaguchi et al. · Nature Medicine · 2001 · 199 citations
Medicine, Neurobiology, Neuroscience +12