Organic Letters · 2012 · 39 citations · 22 references
Bioorganic ChemistryTurn InducerBiochemistryModel TripeptidesProtein FoldingSecond PositionNatural SciencesX-ray StudiesEngineeringHeterocyclicPeptoidPeptide LibraryOrganic ChemistryPeptide SynthesisChemistryHeterocycle ChemistryChemical BiologyMolecular Modeling
In order to investigate the ability of the (S)-aminobicyclo[2.2.2]octane-2-carboxylic acid 1 (H-(S)-ABOC-OH) to induce reverse turns into peptides, two model tripeptides, in which this bicyclic unit was incorporated into the second position, were synthesized and analyzed by FT-IR, CD, NMR, and X-ray studies.
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Samuel H. Gellman · Accounts of Chemical Research · 1998 · 2.5K citations
Engineering, Chemical Analysis, Altmetric Attention Score +17