Grant McNaughton‐Smith

Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics

Stephen Hanessian, Grant McNaughton‐Smith, Henry‐Georges Lombart et al. · Tetrahedron · 1997 · 630 citations

Pharmacy, Biochemistry, Medicinal Chemistry +16

Synthesis of (4S)-hydroxymethyl-(2R)-(2-propyl)-butyrolactone: A quest for a practical route to an important hydroxyethylene isostere chiron

Stephen Hanessian, Teresa Abad-Grillo, Grant McNaughton‐Smith · Tetrahedron · 1997 · 169 citations

Natural Sciences, Chemistry, Medicinal Chemistry +3

N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): A Novel, Selective KCNQ2/Q3 Potassium Channel Activator

Alan D. Wickenden, Jeff Krajewski, Barry London et al. · Molecular Pharmacology · 2007 · 115 citations

Medicine, Neuroscience, Pharmacology +17

In Vivo Profile of ICA-27243 [N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a Potent and Selective KCNQ2/Q3 (Kv7.2/Kv7.3) Activator in Rodent Anticonvulsant Models

Rosemarie Roeloffs, Alan D. Wickenden, Christopher Crean et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 65 citations

Medicine, Neuroscience, Pharmacology +15

A versatile synthesis of a β-turn peptidomimetic scaffold: An approach towards a designed model antagonist of the tachykinin NK-2 receptor

Stephen Hanessian, Grant McNaughton‐Smith · Bioorganic & Medicinal Chemistry Letters · 1996 · 48 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17