Concepedia

Rosemarie Roeloffs

RR

13

Publications

1.1K

Citations

12

H-Index

1988

Active since

Affiliations

Abbott (United States)(Current)

Durham University

Abbott (United Kingdom)

Pfizer (United Kingdom)

Pfizer (United States)

Rosemarie Roeloffs is an author at Abbott (United States) specializing in medicine, pharmacology, and medicinal chemistry.

Top concepts

Publications per year

1988–2019

13

Publications

13

A-803467, a potent and selective Na <sub>v</sub> 1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

Michael F. Jarvis, Prisca Honoré, Char‐Chang Shieh et al. · Proceedings of the National Academy of Sciences · 2007 · 514 citations · Full text

N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): A Novel, Selective KCNQ2/Q3 Potassium Channel Activator

Alan D. Wickenden, Jeff Krajewski, Barry London et al. · Molecular Pharmacology · 2007 · 115 citations

A novel selective and orally bioavailable <scp>N</scp> a <scp> <sub>v</sub> </scp> 1.8 channel blocker, <scp>PF</scp> ‐01247324, attenuates nociception and sensory neuron excitability

C. Elizabeth Payne, Adam R. Brown, Jonathon W Theile et al. · British Journal of Pharmacology · 2015 · 96 citations · Full text

Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Na<sub>v</sub>1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pain

Michael E. Kort, Irene Drizin, Robert J. Gregg et al. · Journal of Medicinal Chemistry · 2008 · 83 citations · Full text

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In Vivo Profile of ICA-27243 [N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a Potent and Selective KCNQ2/Q3 (Kv7.2/Kv7.3) Activator in Rodent Anticonvulsant Models

Rosemarie Roeloffs, Alan D. Wickenden, Christopher Crean et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 65 citations

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