Frequent inactivation of the cyclin-dependent kinase inhibitor p18 by homozygous deletion in multiple myeloma cell lines: ectopic p18 expression inhibits growth and induces apoptosis

Role of the INK4a Locus in Tumor Suppression and Cell Mortality

Manuel Serrano, Han‐Woong Lee, Lynda Chin et al. · Cell · 1996 · 1.6K citations · Full text

Oncology, Cell Mortality, Medicine +11

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.

Kun‐Liang Guan, Christopher W. Davies‐Jenkins, Y Li et al. · Genes & Development · 1994 · 725 citations · Full text

Molecular Biology, Cell Proliferation, Cell Growth +19

A rapid and simple method for the isolation of apoptotic DNA fragments

Martin Herrmann, H.-M. Lorenz, Reinhard Voll et al. · Nucleic Acids Research · 1994 · 657 citations · Full text

Chromatin, Dna Sequencing, Simple Method +12

Novel INK4 Proteins, p19 and p18, Are Specific Inhibitors of the Cyclin D-Dependent Kinases CDK4 and CDK6

Hiroshi Hirai, Martine F. Roussel, Jun‐ya Kato et al. · Molecular and Cellular Biology · 1995 · 645 citations · Full text

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation.

Yue Xiong, H Zhang, David Beach · Genes & Development · 1993 · 512 citations · Full text

Subunit Rearrangement, Molecular Biology, Cell Cycle +21