Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module

Single-channel currents recorded from membrane of denervated frog muscle fibres

Erwin Neher, Bert Sakmann · Nature · 1976 · 2.5K citations

Muscle Physiology, Muscle Function, Single-channel Currents +11

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +10

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy et al. · Cell · 1995 · 2.3K citations · Full text

Long Qt Syndrome, Cardiomyopathy, Genetics +9

Lidocaine block of cardiac sodium channels.

Bruce P. Bean, Charles J. Cohen, Richard W. Tsien · The Journal of General Physiology · 1983 · 657 citations · Full text

Cardiac Muscle, Channelopathies, Mum Lidocaine +15

Electrophysiological Properties of Mutant Na _v 1.7 Sodium Channels in a Painful Inherited Neuropathy

Theodore Cummins, Sulayman D. Dib‐Hajj, Stephen G. Waxman · Journal of Neuroscience · 2004 · 392 citations · Full text