Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress

Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor

Frank R. Stermitz, Peter Lorenz, Jeanne N. Tawara et al. · Proceedings of the National Academy of Sciences · 2000 · 755 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine

Yifei Zhang, Dajin Zou, Wei Liu et al. · The Journal of Clinical Endocrinology & Metabolism · 2008 · 564 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Activation of Signal Transducer and Activator of Transcription 3 Protects Cardiomyocytes from Hypoxia/Reoxygenation-Induced Oxidative Stress Through the Upregulation of Manganese Superoxide Dismutase

Shinji Negoro, Keita Kunisada, Yasushi Fujio et al. · Circulation · 2001 · 257 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

<scp>JAK</scp>2/<scp>STAT</scp>3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury

Yang Yang, Weixun Duan, Zhenxiao Jin et al. · Journal of Pineal Research · 2013 · 230 citations

Life Sciences, Cardiology, Pharmacology +17

JAK/STAT Signaling Is Associated With Cardiac Dysfunction During Ischemia and Reperfusion

Eduardo Mascareno, M. E. El-Shafei, Nilanjana Maulik et al. · Circulation · 2001 · 201 citations · Full text

Medicine, Cardiology, Pharmacology +15