Simultaneous quantitative determination of 5-aza-2′-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors

Publication | Open Access

DOI Full Paper Access

Citations

References

2016

Year

Nicole M. Anders, Jianyong Liu, Teresia Wanjiku, Hugh Giovinazzo, Jianya Zhou, Ajay Vaghasia, William G. Nelson, Srinivasan Yegnasubramanian, Michelle A. Rudek

Journal of Chromatography B

BiochemistryMedicineNatural SciencesBioanalysisMass SpectrometryExposure-response MeasuresMolecular BiologyOligonucleotideDna AnalysisToxicogenomicsAnalytical ChemistryDna DemethylationPharmacologyEpigeneticsNucleic Acid BiomarkersChromatography5-Aza-2′-deoxycytidine Genomic Incorporation