The Oncologist · 2013 · 294 citations · 32 references
MedicinePharmacologyPharmacotherapyCancer PharmacologyChemotherapyClinical PharmacologyHematologic Malignancy PharmacotherapyHematologic Malignancy TherapyMyelodysplastic SyndromesAcute Myeloid Leukemia TherapyChronic Myelomonocytic LeukemiaDrug ReviewHigher-risk Myelodysplastic SyndromesHypomethylating Agent TherapyHypomethylating AgentsMyelodysplastic Syndrome TherapyMyelodysplastic Syndrome Treatment
The introduction of the hypomethylating agents azacitidine and decitabine has been a major advancement in the treatment of patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia who are ineligible for more intensive treatments. This concise drug review summarizes the current state of treatment with azacitidine and decitabine.
32
Pierre Fenaux, Ghulam J. Mufti, Eva Hellström‐Lindberg et al. · The Lancet Oncology · 2009 · 2.6K citations · Full text
Decitabine improves patient outcomes in myelodysplastic syndromes
Hagop M. Kantarjian, Jean‐Pierre J. Issa, C Rosenfeld et al. · Cancer · 2006 · 1.5K citations
Medicine, Hematology, Pharmacology +14
Hagop M. Kantarjian, Xavier Thomas, Anna Dmoszyńska et al. · Journal of Clinical Oncology · 2012 · 1.2K citations · Full text