Journal of Asian Natural Products Research · 2016 · 11 citations · 19 references
Life SciencesBiochemistryBotanyEthnobotanyLipid BiochemistryPlant BiochemistryAromatic PlantsCholinergic PharmacologyLipid ChemistryLipid MetabolismMedicinal PlantsSteroid StructureActive Compound IsolationFree Radical ScavengingLipid Composition AnalysisMass Spectral Data AnalysisMedicinal Aromatic PlantsPharmacological ScreeningPlant SterolsSphingolipid Structure
Chemical investigations on the aerial parts of Carissa opaca resulted in the isolation and characterization of two new nor-triterpenoids (compounds 1 and 2) and a new sphingolipid (compound 3) together with six known compounds. The structures of all the isolates were established using spectral data. All the isolated compounds showed DPPH radical scavenging and enzyme inhibitory activities against enzymes acetylcholinesterase, butyrylcholinesterase, and lipoxygenase.
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A new and rapid colorimetric determination of acetylcholinesterase activity
George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations