Platelet‐Derived S100A8/A9 and Cardiovascular Disease in Systemic Lupus Erythematosus

Abstract

Platelets contain S100A8/A9 in membrane-enclosed vesicles, enabling rapid cell surface deposition upon activation. Furthermore, platelet S100A8/A9 protein levels were increased in SLE patients, particularly in those with CVD, and may be a future therapeutic target.