hTERT promotes the invasion of gastric cancer cells by enhancing FOXO3a ubiquitination and subsequent ITGB1 upregulation - Concepedia

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hTERT promotes the invasion of gastric cancer cells by enhancing FOXO3a ubiquitination and subsequent ITGB1 upregulation

136

Citations

34

References

2015

Year

C. Hu, Zhenghong Ni, Bo–Sheng Li, Yong Xin, Xin Yang, Jianwei Zhang, Dan Zhang, Yong Qin, Mengmeng Jie, Hui Dong,

Abstract

The hTERT/MDM2-FOXO3a-ITGB1 pathway markedly contributes to hTERT-promoted gastric cancer invasion, suggesting that this pathway might be a novel target for the prevention and treatment of gastric cancer metastasis.

References

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