Interaction between the retinoblastoma protein and the oncoprotein MDM2

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

Don W. Cleveland, S G Fischer, Marc W. Kirschner et al. · Journal of Biological Chemistry · 1977 · 5.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +10

Amplification of a gene encoding a p53-associated protein in human sarcomas

Jonathan D. Oliner, Kenneth W. Kinzler, Paul S. Meltzer et al. · Nature · 1992 · 2K citations · Full text

Medicine, Genetics, Molecular Genetics +12

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Jonathan D. Oliner, Jennifer A. Pietenpol, Sam Thiagalingam et al. · Nature · 1993 · 1.5K citations

Medicine, Cancer Biology, Oncology +16

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

Philip W. Hinds, Sibylle Mittnacht, Vjekoslav Dulić et al. · Cell · 1992 · 1K citations

Life Sciences, Molecular Biology, Molecular Genetics +12