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5-Substituted 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidines with anti-proliferative activity as potent and selective inhibitors of cyclin-dependent kinases

Anti-proliferative ActivityMedicinal ChemistryCyclin-dependent KinasesHeterocyclicBiochemistryMedicineNatural SciencesRational Drug DesignPharmacological AgentSelective InhibitorsPharmacotherapyAnti-cancer AgentPharmacologyPharmaceutical ChemistryDrug Discovery