Concepedia

Organocatalytic construction of spirooxindole naphthoquinones through Michael/hemiketalization using<scp>l</scp>-proline derived bifunctional thiourea

V. Pratap Reddy Gajulapalli, Kanduru Lokesh, Manjunatha Vishwanath, Venkitasamy Kesavan

RSC Advances · 2016 · 40 citations · 44 references

DOI

Concepts

Abstract

Michael/hemiketalization of 2-hydroxy-1,4-naphthoquinone to oxindole ketoester was studied using a series of chiral bifunctional organocatalysts.

References

44

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

Matthias Rottmann, Case W. McNamara, Bryan K. S. Yeung et al. · Science · 2010 · 1.2K citations · Full text

, , +16

Chiral Squaramide Derivatives are Excellent Hydrogen Bond Donor Catalysts

Jeremiah P. Malerich, Koji Hagihara, Viresh H. Rawal · Journal of the American Chemical Society · 2008 · 942 citations · Full text

, , +15

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

Warren R. J. D. Galloway, Albert Isidro‐Llobet, David R. Spring · Nature Communications · 2010 · 869 citations · Full text

, , +14

Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors

Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska et al. · Journal of the American Chemical Society · 2005 · 649 citations

, , +12

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

Xiaohua Chen, Qiang Wei, Shi‐Wei Luo et al. · Journal of the American Chemical Society · 2009 · 572 citations

, , +14