Hypolipidemic activity of Mimosa pudica Linn on Butter Induced Hyperlipidemia in Rats

Abstract

The hypolipidemic activity of Mimosa pudica extract was studied on high fat diet induced models of hyperlipidemia in rats. Hyperlipidemia in experimental rats evidenced by an enhancement in the levels of Cholesterols, Triglycerides, LDL and VLDL. Ehanol extract showed significant hypolipidemic effect by lowering the serum levels of biochemical parameters such as significant reduction in the level of serum Cholesterol, TG, LDL, VLDL and increase in HDL level which was similar to the standard drug Lovastatin. Preliminary phytochemical analysis revealed the presence of phytoconstituents such as steroids, flavonoids, glycosides, alkaloids and phenolic compounds.