Bringing nitrilase sequences from databases to life: the search for novel substrate specificities with a focus on dinitriles

Creation of a Productive, Highly Enantioselective Nitrilase through Gene Site Saturation Mutagenesis (GSSM)

Grace DeSantis, Kelvin K. L. Wong, Bob Farwell et al. · Journal of the American Chemical Society · 2003 · 258 citations

Engineering, Amino Acids, Molecular Biology +18

Exploring Nitrilase Sequence Space for Enantioselective Catalysis

Dan E. Robertson, Jennifer A. Chaplin, Grace DeSantis et al. · Applied and Environmental Microbiology · 2004 · 229 citations · Full text

The Arabidopsis thaliana Isogene NIT4 and Its Orthologs in Tobacco Encode β-Cyano-l-alanine Hydratase/Nitrilase

Markus Piotrowski, Sabine Schönfelder, Elmar W. Weiler · Journal of Biological Chemistry · 2001 · 199 citations · Full text

Plant Physiology, Genetics, Molecular Biology +19

Enzymatic characterization of the recombinant Arabidopsis thaliana nitrilase subfamily encoded by the NIT 2/ NIT 1/ NIT 3-gene cluster

Sonja Vorwerk, Stephanie Biernacki, Helke Hillebrand et al. · Planta · 2001 · 166 citations

Plant Molecular Biology, Plant Genetics, Biosynthesis +13

Microbial nitrilases: versatile, spiral forming, industrial enzymes

R.N. Thuku, Dean Brady, Michael J. Benedik et al. · Journal of Applied Microbiology · 2008 · 150 citations

Engineering, Molecular Biology, Microbial Physiology +16