Concepedia

Human umbilical cord-derived mesenchymal stem cells suppress proliferation of PHA-activated lymphocytes in vitro by inducing CD4+CD25highCD45RA+ regulatory T cell production and modulating cytokine secretion

Hongna Yang, Jinhua Sun, Yan Li, Wei-Ming Duan, Jianzhong Bi, Tingyu Qu

Cellular Immunology · 2016 · 50 citations · 16 references

DOI

Concepts

References

16

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

Weihong Liu, Amy Putnam, Gregory L. Szot et al. · The Journal of Experimental Medicine · 2006 · 2.6K citations · Full text

, , +17

Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications

Soufiane Ghannam, Carine Bouffi, Farida Djouad et al. · Stem Cell Research & Therapy · 2010 · 506 citations · Full text

, , +17

Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells

Patricia Luz‐Crawford, Mónica Kurte, Javiera Bravo‐Alegria et al. · Stem Cell Research & Therapy · 2013 · 501 citations · Full text

, , +17

Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus

Lingyun Sun, Dandan Wang, Jun Liang et al. · Arthritis & Rheumatism · 2010 · 481 citations

, , +16

Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion

Petra Hoffmann, Ruediger Eder, Tina J. Boeld et al. · Blood · 2006 · 410 citations

, , +13