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Correlating the Impact of Well-Defined Oligosaccharide Structures on Physical Stability Profiles of IgG1-Fc Glycoforms

Apurva S. More, Vishal M. Toprani, Solomon Z. Okbazghi, Sangeeta B. Joshi, C. Russell Middaugh, Thomas J. Tolbert, David B. Volkin

Journal of Pharmaceutical Sciences · 2015 · 28 citations · 39 references

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39

Structural Analysis of Human IgG-Fc Glycoforms Reveals a Correlation Between Glycosylation and Structural Integrity

S. Krapp, Yusuke Mimura, Roy Jefferis et al. · Journal of Molecular Biology · 2003 · 664 citations

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The impact of glycosylation on monoclonal antibody conformation and stability

Kai Zheng, Christopher Bantog, Robert Bayer · mAbs · 2011 · 336 citations · Full text

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Role of Oligosaccharide Residues of IgG1-Fc in FcγRIIb Binding

Yusuke Mimura, Peter Sondermann, Rodolfo Ghirlando et al. · Journal of Biological Chemistry · 2001 · 238 citations · Full text

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Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans

Marcella Yu, Darren L. Brown, Chae Reed et al. · mAbs · 2012 · 209 citations · Full text

, , +17

Marketing approval of mogamulizumab

Alain Beck, Janice M. Reichert · mAbs · 2012 · 208 citations · Full text

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