Structural Characterization of IgG1 mAb Aggregates and Particles Generated Under Various Stress Conditions

Srivalli Telikepalli, Ozan S. Kumru, Cavan Kalonia, +4

Journal of Pharmaceutical Sciences

Structural CharacterizationVarious Stress ConditionsProtein FoldingGlycobiologyImmunology +6

Compatibility, Physical Stability, and Characterization of an IgG4 Monoclonal Antibody After Dilution into Different Intravenous Administration Bags

Ozan S. Kumru, Jun Liu, Junyan A. Ji, +6

Journal of Pharmaceutical Sciences

ImmunohematologyPhysical StabilityImmunocytochemical TechniqueAllergyMedicine +10

Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice

Neil C. Dalvie, Sergio A. Rodriguez‐Aponte, Brittany L. Hartwell, +41

Proceedings of the National Academy of Sciences

Viral PathogenesisImmunologyImmunodominanceViral Structural ProteinBroad-spectrum Vaccines +17

Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity

Jayant Arora, Yue Hu, Reza Esfandiary, +6

mAbs

Anthrax vaccine powder formulations for nasal mucosal delivery

Ge Jiang, Sangeeta B. Joshi, Laura J. Peek, +12

Journal of Pharmaceutical Sciences

VaccinationMucosal VaccinationNasal Mucosal DeliveryTherapeutic VaccineVaccine Design +2

Properties of Synthetic Spider Silk Fibers Based on Argiope aurantia MaSp2

Amanda E. Brooks, Shane M. Stricker, Sangeeta B. Joshi, +3

Biomacromolecules

A Formulation Development Approach to Identify and Select Stable Ultra–High-Concentration Monoclonal Antibody Formulations With Reduced Viscosities

Neal Whitaker, Jian Xiong, Samantha E. Pace, +4

Journal of Pharmaceutical Sciences

Formulation Development ApproachReduced ViscositiesImmunologyPharmaceutical TechnologyDrug Delivery Systems +6

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

Payton A. Weidenbacher, Mrinmoy Sanyal, Natalia Friedland, +17

Nature Communications

VaccinationCross-protectionVaccine DevelopmentVaccine TargetImmunology +11

Induction of direct somatic embryogenesis and plant regeneration in pepper (Capsicum annuum L.)

Marla L. Binzel, N. Sankhla, Sangeeta B. Joshi, +1

Plant Cell Reports

BiologyDevelopmental BiologyEngineeringBotanyDirect Somatic Embryogenesis +7

Comparison of High-Throughput Biophysical Methods to Identify Stabilizing Excipients for a Model IgG2 Monoclonal Antibody: Conformational Stability and Kinetic Aggregation Measurements

Weiqiang Cheng, Sangeeta B. Joshi, Feng He, +5

Journal of Pharmaceutical Sciences

Biophysical ModelingImmunocytochemical TechniqueProtein FoldingNatural SciencesBioanalysis +10