Concepedia

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

Christof Angermueller, Stephen J. Clark, Heather Lee, Iain C. Macaulay, Mabel Teng, Xiaoming Hu, Felix Krueger, Sébastien A. Smallwood, Chris P. Ponting, Thierry Voet,

Nature Methods · 2016 · 748 citations · 25 references

DOIFull text

Open access

Concepts

References

25

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 94.7K citations · Full text

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Cole Trapnell, Brian A. Williams, Geo Pertea et al. · Nature Biotechnology · 2010 · 16.1K citations

, , +10

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

Felix Krueger, Simon Andrews · Bioinformatics · 2011 · 5.6K citations · Full text

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.2K citations · Full text

, , +9

Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells

Allon M. Klein, Linas Mažutis, Ilke Akartuna et al. · Cell · 2015 · 3.6K citations · Full text

, , +12