Concepedia

Neurogranin restores amyloid β-mediated synaptic transmission and long-term potentiation deficits

Kanwardeep S. Kaleka, Nashaat Z. Gerges

Experimental Neurology · 2015 · 32 citations · 49 references

DOI

Concepts

References

49

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva et al. · Nature · 2002 · 4.3K citations

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Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Ganesh M. Shankar, Shaomin Li, Tapan Mehta et al. · Nature Medicine · 2008 · 3.7K citations · Full text

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beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

MP Mattson, Bin Cheng, David L. Davis et al. · Journal of Neuroscience · 1992 · 1.6K citations · Full text

, , +17

APP Processing and Synaptic Function

Flavio Kamenetz, Taisuke Tomita, Helen Hsieh et al. · Neuron · 2003 · 1.6K citations · Full text

, , +13

Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway

Ganesh M. Shankar, Brenda L. Bloodgood, Matthew Townsend et al. · Journal of Neuroscience · 2007 · 1.6K citations · Full text

, , +17