Concepedia

Dioscin alleviates BDL- and DMN-induced hepatic fibrosis via Sirt1/Nrf2-mediated inhibition of p38 MAPK pathway

Li-Na Gu, Xufeng Tao, Youwei Xu, Xu Han, Yan Qi, Lina Xu, Lianhong Yin, Jinyong Peng

Toxicology and Applied Pharmacology · 2015 · 118 citations · 50 references

DOI

Concepts

References

50

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications · 1997 · 4K citations

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Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text

, , +14

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature Medicine · 2006 · 1.3K citations

, , +14

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

Christopher J. Harvey, Rajesh K. Thimmulappa, Anju Singh et al. · Free Radical Biology and Medicine · 2008 · 528 citations

, , +16

Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

Paul Nioi, Michael McMahon, Ken Itoh et al. · Biochemical Journal · 2003 · 497 citations · Full text

, , +15