Concepedia

DNA methylation reactivates GAD1 expression in cancer by preventing CTCF-mediated polycomb repressive complex 2 recruitment

Hongli Yan, Ge Tang, Huaiming Wang, Tong He, Xiaochen Sun, A H Ting, Anmei Deng, Shuhan Sun

Oncogene · 2015 · 51 citations · 44 references

DOI

Concepts

References

44

Capturing Chromosome Conformation

Job Dekker, Karsten Rippe, Martijn Dekker et al. · Science · 2002 · 3.8K citations

, , +17

Perceptions of epigenetics

Adrian Bird · Nature · 2007 · 2.9K citations · Full text

DNA Modification Mechanisms and Gene Activity During Development

R. Holliday, J. E. Pugh · Science · 1975 · 1.9K citations

, , +10

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

Adam C. Bell, Gary Felsenfeld · Nature · 2000 · 1.7K citations

, , +14

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

Amy T. Hark, Christopher J. Schoenherr, David J. Katz et al. · Nature · 2000 · 1.5K citations

, , +14