Concepedia

Polycomb-mediated Silencing

Polycomb-Mediated Silencing is a chromatin regulatory mechanism that belongs to the class of epigenetic silencing processes and is distinguished by the targeted repression of gene expression through the action of Polycomb group protein complexes, which catalyze histone modifications leading to the establishment and maintenance of facultative heterochromatin.

261

Publications

42.5K

Citations

1.7K

Authors

511

Institutions

Publications per year

2017–2026

67

Variants

Polycomb-mediated Repression

Parents

Publications

261

Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

Ru Cao, Liangjun Wang, Hengbin Wang et al. · Science · 2002 · 3.8K citations

, , +16

Role of histone H2A ubiquitination in Polycomb silencing

Hengbin Wang, Liangjun Wang, Hediye Erdjument‐Bromage et al. · Nature · 2004 · 1.8K citations

, , +12

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

Jing Zhao, Bryan K. Sun, Jennifer A. Erwin et al. · Science · 2008 · 1.6K citations · Full text

, , +17

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

Kyoko L. Yap, SiDe Li, Ana M. Muñoz-Cabello et al. · Molecular Cell · 2010 · 1.4K citations · Full text

, , +17

The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing

Francesca De Santa, Maria Grazia Totaro, Elena Prosperini et al. · Cell · 2007 · 953 citations · Full text

, , +12

1–5 of 261

Authors

1.7K

  1. NB
    Neil Brockdorff

    University of Oxford, United Kingdom

    11 publications · 3.5K citations

    11

    h-index

  2. CD
    Caroline Dean

    John Innes Centre, United Kingdom

    11 publications · 1.7K citations

    11

    h-index

  3. VP
    Vincenzo Pirrotta

    Rutgers, The State University of New Jersey, United States

    10 publications · 1.4K citations

    10

    h-index

  4. JM
    Jürg Müller

    Max Planck Institute of Biochemistry, Germany

    8 publications · 1.7K citations

    8

    h-index

  5. RS
    Richard S. Jones

    Centers for Disease Control and Prevention, United States

    8 publications · 6.4K citations

    8

    h-index

1–5 of 1.7K

Institutions

511

  1. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    20 publications

    1.9K citations

  2. Harvard University

    Cambridge, United States

    14 h-index

    15 publications

    4.4K citations

  3. John Innes Centre

    Norwich, United Kingdom

    13 h-index

    13 publications

    2.2K citations

  4. University of Geneva

    Geneva, Switzerland

    13 h-index

    13 publications

    1.5K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    13 publications

    4K citations

  6. Inserm

    Paris, France

    12 h-index

    13 publications

    1.4K citations

  7. University of Oxford

    Oxford, United Kingdom

    11 h-index

    11 publications

    2.4K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    10 h-index

    10 publications

    6.9K citations

1–8 of 511

Venues

  1. Molecular Cell

    19 publications · 5.1K citations

    19

    h-index

  2. Development

    12 publications · 2.1K citations

    12

    h-index

  3. Molecular and Cellular Biology

    MCB · 12 publications · 1.3K citations

    12

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 2K citations

    12

    h-index

  5. Nature Communications

    10 publications · 844 citations

    10

    h-index

1–5