Concepedia

Modular organization of Interleukin-6 and Interleukin-11 α-receptors

Rebecca Nitz, Juliane Lokau, Samadhi Aparicio-Siegmund, Jürgen Scheller, Christoph Garbers

Biochimie · 2015 · 29 citations · 25 references

DOI

Concepts

References

25

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

Martina Fischer, Jutta Goldschmitt, Christian Peschel et al. · Nature Biotechnology · 1997 · 538 citations

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Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)

Vance B. Matthews, Björn Schuster, Stefan Schütze et al. · Journal of Biological Chemistry · 2003 · 385 citations · Full text

, , +9

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

Athena Chalaris, Björn Rabe, Krzysztof Paliga et al. · Blood · 2007 · 323 citations · Full text

, , +14

Cloning of a murine IL‐11 receptor alpha‐chain; requirement for gp130 for high affinity binding and signal transduction.

Douglas J. Hilton, Adrienne A. Hilton, A. Raicevic et al. · The EMBO Journal · 1994 · 283 citations · Full text

, , +4

The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site.

Jürgen Müllberg, Walter OBERTHÜR, F. Lottspeich et al. · The Journal of Immunology · 1994 · 268 citations

, , +15