Samadhi Aparicio-Siegmund

The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases

Christoph Garbers, Niloufar Monhasery, Samadhi Aparicio-Siegmund et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2014 · 152 citations

Inflammation, Cytokine, Molecular Immunology +8

Proteolytic Cleavage Governs Interleukin-11 Trans-signaling

Juliane Lokau, Rebecca Nitz, Maria Agthe et al. · Cell Reports · 2016 · 130 citations · Full text

Inflammatory Lung Disease, Il-6 Receptor, Immunology +16

An Interleukin-6 Receptor-dependent Molecular Switch Mediates Signal Transduction of the IL-27 Cytokine Subunit p28 (IL-30) via a gp130 Protein Receptor Homodimer

Christoph Garbers, Björn Spudy, Samadhi Aparicio-Siegmund et al. · Journal of Biological Chemistry · 2012 · 125 citations · Full text

Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR)

Christoph Garbers, Fabian Kuck, Samadhi Aparicio-Siegmund et al. · Cell Cycle · 2013 · 65 citations · Full text

Inflammation, Mtor Activation, Mammalian Target +14

Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling

Charlotte M. Flynn, Yvonne Garbers, Juliane Lokau et al. · Scientific Reports · 2019 · 64 citations · Full text