Christoph Garbers

Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells

Sylvia Heink, Nir Yogev, Christoph Garbers et al. · Nature Immunology · 2016 · 387 citations

Life Sciences, Cell Biology, Immunology +14

Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease

Stefan Schreiber, Konrad Aden, Joana P. Bernardes et al. · Gastroenterology · 2021 · 250 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Inhibition of Classic Signaling Is a Novel Function of Soluble Glycoprotein 130 (sgp130), Which Is Controlled by the Ratio of Interleukin 6 and Soluble Interleukin 6 Receptor

Christoph Garbers, Wolfgang Thaiss, Gareth W. Jones et al. · Journal of Biological Chemistry · 2011 · 208 citations · Full text

Life Sciences, Immunology, Pharmacology +12

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

Christoph Garbers, Nathalie Jänner, Athena Chalaris et al. · Journal of Biological Chemistry · 2011 · 196 citations · Full text

Life Sciences, Cell Biology, Pathology +7

Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment

Claudia M. Wunderlich, Philipp Ackermann, Anna Lena Ostermann et al. · Nature Communications · 2018 · 176 citations · Full text

Life Sciences, Immunology, Oncology +17